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KMID : 0361420080320010116
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Journal of Korean Academy of Rehabilitation Medicine
2008 Volume.32 No. 1 p.116 ~ p.118
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A Case of Fluoxeine Induced Mania in Poststroke Depression Patient - A case report -
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Cho Ye-Rim
Lee Jong-In
Kim Hye-Won
Woo Young-Sup
Lee Jung-Soo
Yoon Jong-Su
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Abstract
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Poststroke depression is very common and has been reported in as many as 40~50% of poststroke patients. The fluoxetine is one of the most frequently prescribed drugs for the treatment of poststroke depression. This serotonin selective reuptake inhibitor, known as generally safe and well tolerated drug, has been recently reported to induce mania. We report a case of fluoxetine-induced mania. A 64 year-old male, who has taken 10 mg of fluoxetine daily due to poststroke depression, presented elevated mood, hyperactivity, regressed behavior, excessive planning, sleep deterioration, and talkativeness abruptly. We were suspicious of fluoxetine- induced manic state and discontinued immediately fluoxetine without prescription of mood stabilizer. His symptoms had been ceased over two weeks.
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KEYWORD
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Fluoxetine, Mania, Poststroke depression
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